Check out the latest LGS Research News.
First published: May 15, 2026
Real-world outcomes of responsive neurostimulation in patients with Lennox–Gastaut syndrome: A multicenter retrospective study Lennox–Gastaut syndrome (LGS) involves several different seizure types and developmental differences, and for most families, the hardest part is that LGS seizures rarely respond well to…
Reflections from the 10th International LGS Foundation Family & Professional Conference
I came to Orlando as a first-time attendee, still relatively new to the LGS community. I am leaving inspired, hopeful, and more energized about the future of LGS research than I have ever been. Over three days, we laughed and…
For families living with Lennox-Gastaut Syndrome (LGS), every day can feel like a battle against the unpredictable. New research is moving beyond traditional surgery and heavy prescriptions, opening a path toward non-invasive options that could fundamentally change how we treat…
The Lennox-Gastaut Syndrome (LGS) Foundation and the National Organization for Rare Disorders (NORD) launched a study with global reach to research LGS and LGS-Related Developmental and Epileptic Encephalopathies (LGS-DEE), which are a group of rare diseases characterized by uncontrolled seizures,…
From seizures to full lives through precision diagnoses, precision treatments, and whole‑life care Every family living with Lennox‑Gastaut Syndrome knows how hard this journey can be—and how deeply we all dream of better answers and brighter days. That’s why the…
First published: February 8, 2025
Vagus nerve stimulation therapy in Lennox-Gastaut syndrome (severe childhood epilepsy): plain language summary of a 2-year study Surgical interventions are one form of therapy for LGS patients and include cortical resection (resection), corpus callosotomy (callosotomy), or device therapy. Therapeutic neuromodulation…
First published: November 24, 2025
EEG functional connectivity as a marker of evolution from infantile epileptic spasms syndrome to Lennox–Gastaut Syndrome Early diagnosis and effective treatment significantly improve LGS outcomes and reduce costs. However, LGS diagnosis is difficult, relies on a combination of EEG features…
Highlights from the 2025 American Epilepsy Society Annual Meeting
The 2025 American Epilepsy Society (AES) Annual Meeting took place December 5–9 in Atlanta, Georgia, bringing together nearly 6,000 epilepsy clinicians, researchers, advocates, and industry partners from more than 60 countries. Across the meeting, Lennox-Gastaut syndrome (LGS) was a clear…
A long-term care planning needs assessment
Overview The LGS Foundation recently participated in a new study, published in Epilepsy & Behavior, which focused on the perspectives of caregivers who are planning for the adulthood of patients with Developmental and Epileptic Encephalopathies (DEE). The anonymous, internet-based survey…
When great minds meet, great breakthroughs happen!
The 2025 LGS Research Meeting of the Minds, held July 21–22, brought together over 100 caregivers, healthcare professionals, researchers, and industry partners committed to improving care for individuals living with Lennox-Gastaut Syndrome (LGS) and associated developmental and epileptic encephalopathies (DEEs)….
